Four cars were involved in smash close to Pontefract town centre.
Police said three people have been injured but that no one was trapped in any of the vehicles.
A BMW 520, a Ford Fiesta, a Kia and a Nissan X-Trail were all involved in the smash, on Mill Hill Road, just before 12.30pm today (Monday).
Emergency services are at the scene and the road is blocked.
Police said diversions are in place.