Castleford Tigers duo Michael Shenton and Daryl Clark have been selected in the England side to face Samoa in the opening game of the Four Nations at the Suncorp Stadium, Brisbane on Saturday.
Tigers skipper Shenton will start at centre while Clark is set to make his England debut off the bench.
Also in the 17-man team are former Castleford players Joe Westerman – also set to make his debut - and Brett Ferres.
Westerman steps in at loose forward as England captain Sean O’Loughlin will miss the Samoa match. The Wigan Warriors forward has a problem with his quad sustained in the First Utility Super League Grand Final 11 days ago and has been unable to recover in time for the match in Queensland.
Canterbury-Bankstown Bulldogs prop James Graham will take over the captaincy – a role he did during England’s 2010 Four Nations campaign in the southern hemisphere, when he replaced the injured Adrian Morley for the duration of that tournament.
O’Loughlin is making good recovery and is expected to figure in England’s second match against Australia in Melbourne on November 2.
England coach Steve McNamara said:“It is a shame that Sean (O’Loughlin) misses the match with a problem with his quad.
“The Samoa match has come too soon, but we remain confident he’ll be ready for Australia the week after.
“James Graham will take over the captaincy for this game. He is a great leader and we saw that with the Bulldogs this season in the NRL where he single-handedly led them to a Grand Final.
“He leads by example and gives 100 per cent effort in everything he does. He inspires everyone around him to follow his lead.
“We have four players in the squad making debut. They are ready. They’ve been in our system for a long time. All four have been in great form during the Super League season.
“There is a slight evolution to the squad this year with some new faces on show. The debutants are exciting and they can prove themselves on the international stage.”
The match will be broadcast live on BBC2 with the programme starting at 6.30am (BST).
Four Nations highlights will be broadcast on BBC1 at 1pm (BST) on Saturday.
The England side to face Samoa at Suncorp Stadium, Brisbane on Saturday October 25, kick off 4.00pm (local) is as follows (professional club and community club in brackets):
Sam Tomkins (Wigan Warriors, Wigan St Patricks)
Josh Charnley (Wigan Warriors, Wigan St Patricks)
Kallum Watkins (Leeds Rhinos, Latchford Albion)
Michael Shenton (Castleford Tigers, Upton)
Ryan Hall (Leeds Rhinos, Oulton Raiders)
Gareth Widdop (St George Illawarra Dragons, King Cross)
Matty Smith (Wigan Warriors, Blackbrook)
George Burgess (South Sydney Rabbitohs, Dewsbury Moor)
Josh Hodgson (Hull KR, East Hull)
James Graham (captain) (Canterbury-Bankstown Bulldogs, Blackbrook)
Liam Farrell (Wigan Warriors, Wigan St Patricks)
Joel Tomkins (Wigan Warriors, Wigan St Patricks)
Joe Westerman (Hull FC, Featherstone Lions)
Daryl Clark (Castleford Tigers, Fryston Warriors)
Brett Ferres (Huddersfield Giants, Smawthorne Panthers)
Tom Burgess (South Sydney Rabbitohs, Dewsbury Moor)
Chris Hill (Warrington Wolves, New Spring Lions)